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When heart damage is suspected, such as a myocardial infarction, the doctor
orders blood tests, some of which are called cardiac enzymes. They consist
of LDH (lactate dehydrogenase) CK (creatine phosphokinase) and AST, formerly
SGOT (I forget!). These enzymes catalyze reactions that help heart muscle
contract and to get energy to the muscle. LDH is found in almost all tissue
cells and when tissue is damaged it leaks into the serum. When heart tissue
is damaged the level may rise up to 10 times normal, but 6-8 times normal is
most common. The same holds true for the other enzymes. An increased level
indicates tissue damage.
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