Guilain Barret Syndrome
Tell me all you cana bout Guilain-Barret Syndrome
Guillain Barre syndrom (GBS) is a paralysing disease,
affecting the limbs and sometimes respiration, which
is thought to be an auto-immune disease. That means
that the body produces antibodies that recognise one's
own antigens, and degrade self-tissue, something that
normally should not happen. The tissue that is
degraded is the myellin around neurons, so that the
nerves cannot pass neurological signals correctly. So
although the disease is paralysing, the muscles are
not affected but the nerves are.
The disease is thought to be caused by infections with
certain viruses or bacteria, and that during that
infection the 'wrong' antibodies are produced. The
symptoms of GBS can start when the infection is
already gone so then it becomes difficult to prove
what was the cause. Who is at risk to get GBS (not
every infected patient develops this syndrom) is not
known at present. Of all GBS cases caused after a
bacterial infection, most follow an enteritis caused
by Campylobacter jejuni, especially a certain serotype
(or serotypes) of C. jejuni.
the patients can be treated by dilution of their
antibodies in their blood, and if necessary receive
respiration. Most patients recover completely however
10 to 15% may suffer long-term effects. Without
treatment GBS can be lethal.
Campylobacer jejuni infections are caused by
contaminated food (especially poultry meat but not
eggs) when this is not correctly heated, or by
contaminated water or milk (unpasteurized). C. jejuni
is a common cause of diarrhea but only specific
serotypes are at risk for developing GBS, and these,
fortunately, are relatively rare.
Guilain Barret syndrome is also called radiculoneurithis.
It is an infectious disease caused by a virus The main
simptoms are muscular weakness, loss of reflexes,
high amount of protein in the liquor.
Usually there are no fever , or pain, but it is a very
serious disease and at the first suspicion of the
ilness one must look as soon as possible for
Thaks for asking NEWTON!
(Dr. Mabel Rodrigues)
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Update: June 2012