Blood DNA Source
Country: United States
Date: March 2005
When extracting DNA from whole blood, is the DNA coming
from the white blood cells since red blood cells do not have nuclei?
I worked in paternity testing lab for three years, so I know the
answer to this. The answer is yes.
Ron Baker, Ph.D.
You are correct that red blood cells, lacking a nucleus, also lack DNA. When
a DNA laboratory receives a sample of blood in a test tube, the sample is
put in a centrifuge to spin, to separate the red cells from the rest of the
blood. The DNA is extracted from the fraction containing the white blood
Sarina Kopinsky, MSc, CGC
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Update: June 2012