E. coli DNA
Country: United States
Date: June 2006
What is the difference between genome and
plasmid of E.coli.? Is the DNA in plasmid be considered as a part of genome?
They are both part of the whole genome of the bacteria. Since
scientists have genome databases just for plasmids, there is some sense
in considering the plasmid genome separate from the single bacterial
chromosome. The whole genome being ALL the DNA sequences of the
The genome of *E. coli* is a single,circular DNA molecule comprised of about
4 million base pairs encoding approximately 3,000 genes. Typical bacterial
plasmids are circular DNA molecules containing around 50,000 base pairs.
Since some strains of bacteria do not contain plasmids, they are not a an
essential part of the genome.
Ron Baker, Ph.D.
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Update: June 2012