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Name: Ana		
Status: Student
Grade:  9-12
Location: VA
Country: United States
Date: March 2007

Which are the cells in our body expressing the most DNA?

This may be a more complicated question than you might think. Our body's DNA is made up of lots of different regions, some of which code proteins, some of which code 'control sequences' that regulate how proteins are made, some of which aren't used at all, and other sections that we aren't sure what they do. Moreover, some segments of DNA have multiple jobs; they are used for one purpose in one cell and for another purpose in another cell. All of these complicated, overlapping roles are part of the reason it's so hard to unlock DNA's mysteries.

To answer your question best, some clarification might help. In biology, we do not say DNA is "expressed". Proteins are "expressed", not DNA. Are you wanting to know which cells use the most DNA (e.g. uses X% of its DNA)? This is an exceedingly difficult question to answer with certainty. Or are you asking which cells express the largest number of proteins (or the greatest amount of protein)? If that's the case, I would point to rapidly growing cells like cancer cells. Or, you might mean which cells have the most potential to turn into other cells (e.g. still have access to their entire set of DNA) -- that's an active area of research, especially with stem cells.


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