Date: September 2007
Could you please explain the distinction between
"smooth" and "rough" Gram-negative bacteria, such as Pseudomonas
aeruginosa, and how it relates to presence or absence of
exopolysaccharide or alginate.
I always had the impression that
the smooth or mucoid strains are those that hyperproduce
alginate; however, I just read that non-mucoid P. aeruginosa
have "smooth" lipopolysaccharide.
A mucoid coat is made up of glycoprotein, a sugar containing
protein molecule. A lipolysaccharide coat (found in smooth
pnemococcus, for example) is made up of fatty acids and sugar
Ron Baker, Ph.D.
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