Chromosome Recognition in Meiosis I
Location: Outside U.S.
Date: January 2009
How does the homologous chromosomes recognize each other in Meisosi I pairings?
That is a great question. The research is showing that each chromosome unzips a small
region of its DNA and they bind together there because of opposite base pairing. There
seem to be enzymes that coordinate this process.
My guess would be by base pairing between the sense strand of one chromosome and the
anti-sense strand of the homologous chromosome. This assumes that the strands of each of
the homologous chromosomes unwind and are available for Hydrogen bonding to a complementary
strand using the Watson-Crick rules for base pairing (A-T & G-C). This base pairing between
complementary strands of homologous chromosomes is probably the physical basis for
crossing-over between homologous chromosomes.
Ron Baker, Ph.D.
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Update: June 2012