Department of Energy Argonne National Laboratory Office of Science NEWTON's Homepage NEWTON's Homepage
NEWTON, Ask A Scientist!
NEWTON Home Page NEWTON Teachers Visit Our Archives Ask A Question How To Ask A Question Question of the Week Our Expert Scientists Volunteer at NEWTON! Frequently Asked Questions Referencing NEWTON About NEWTON About Ask A Scientist Education At Argonne Fatigue and Cell Membranes
Name: Matt
Status: Educator
Grade:  Other
Location: CA
Country: United States
Date: Summer 2010

What makes the cell membrane less permeable as fatigue sets in?


There are publications that mention the function of levorin which induces permeable channels for free radicals to flow through cell membranes. Levorin also decreases surface tensions of aqueous solutions which aids in increasing cell efficiencies and blood flow during muscle activity. In the case of extensive exercise, there seems to be an increase of free radicals by lipid peroxidation that overwhelm cellular antioxidant defenses, resulting in fatigue and lower physical efficiency. In short, it's an increase of free radicals by lipid peroxidation that hinder levorin from inducing permeable channels through the cell membrane.

"An aromatic heptaene antibiotic levorin and its derivatives in muscle activity" [Kurbanov OG, Kasumov KhM.]

"Production, detection, and adaptive responses to free radicals in exercise." [Sachdev S, Davies KJ.]

Alex Viray

Click here to return to the Molecular Biology Archives

NEWTON is an electronic community for Science, Math, and Computer Science K-12 Educators, sponsored and operated by Argonne National Laboratory's Educational Programs, Andrew Skipor, Ph.D., Head of Educational Programs.

For assistance with NEWTON contact a System Operator (, or at Argonne's Educational Programs

Educational Programs
Building 360
9700 S. Cass Ave.
Argonne, Illinois
60439-4845, USA
Update: June 2012
Weclome To Newton

Argonne National Laboratory