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Name: Gentaw
Status: student
Grade: 12+
Location: Outside U.S.
Country: Ethiopia
Date: Spring 2014


Question: Which is the largest IG(antibody)? Does it size have any significance?



Replies:
The largest immunoglobulin class is IgM, which is a pentameric protein. Each Y shaped antibody sub-unit is approximately 150 kDa, which makes the IgM approximately 750 kDa. The advantage of the size is a higher binding capability to the antigen.

Judy Luke



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